SCHEMBL10458474

SCHEMBL10458474

CCO[Si](O)(O)Oc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.41
MAPT P10636 1/20 0.37
CA4 P22748 1/20 0.36
LMNA P02545 1/20 0.35
ALDH1A1 P00352 1/20 0.34
RECQL P46063 1/20 0.34
AOC2 O75106 2/20 0.34
MAOA P21397 2/20 0.34
MAOB P27338 2/20 0.34
DAO P14920 1/20 0.34
NPC1 O15118 1/20 0.34
HPGD P15428 1/20 0.34
CRHBP P24387 1/20 0.34
RAB9A P51151 1/20 0.34
CRHR2 Q13324 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
TSHR P16473 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5801997 0.81 LTA4H (0.50) LTA4HLMNAALDH1A1RECQLMAOA
SCHEMBL896125 0.79 LTA4H (0.45) LTA4HMAPTCA4LMNAALDH1A1
SCHEMBL28044851 0.79 TAAR1 (0.39) LTA4HALDH1A1RECQLAOC2MAOA
SCHEMBL1609097 0.78 LTA4H (0.43) LTA4HMAPTCA4LMNAALDH1A1
SCHEMBL766451 0.78 LTA4H (0.43) LTA4HMAPTCA4LMNAALDH1A1
SCHEMBL5391039 0.78 LTA4H (0.43) LTA4HMAPTCA4LMNAALDH1A1
SCHEMBL5395765 0.77 LTA4H (0.42) LTA4HMAPTCA4ALDH1A1NPC1
SCHEMBL5397165 0.77 LTA4H (0.42) LTA4HMAPTCA4LMNAALDH1A1
SCHEMBL5405845 0.77 LTA4H (0.42) LTA4HMAPTCA4LMNAALDH1A1
SCHEMBL27746358 0.76 CA4 (0.46) LTA4HMAPTCA4LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4891411-A Process for producing olefin polymers and catalyst used therein SUMTIOMO CHEMICAL COMPANY, LIMITED (JP) 1990-01-02 US disclosed
US-4771023-A Process for producing olefin polymers and catalyst used therein SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-09-13 US disclosed
EP-0206817-A1 Catalyst for producing olefin polymers and polymerization process using the catalyst SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-12-30 EP disclosed