Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28044888 | 1.00 | KMT2A (0.53) | KMT2AMEN1L3MBTL1ACHEALDH1A1 | |
| SCHEMBL8371593 | 0.90 | ACHE (0.63) | KMT2AMEN1L3MBTL1ACHEALDH1A1 | |
| SCHEMBL30575027 | 0.90 | ACHE (0.63) | KMT2AMEN1L3MBTL1ACHEALDH1A1 | |
| SCHEMBL28037618 | 0.87 | KMT2A (0.71) | KMT2AMEN1L3MBTL1ACHEALDH1A1 | |
| SCHEMBL8407376 | 0.87 | KMT2A (0.71) | KMT2AMEN1L3MBTL1ACHEALDH1A1 | |
| SCHEMBL8407551 | 0.84 | TDP1 (0.67) | KMT2AMEN1L3MBTL1ACHEALDH1A1 | |
| SCHEMBL28037446 | 0.84 | KMT2A (0.53) | KMT2AMEN1L3MBTL1ALDH1A1GAA | |
| SCHEMBL28037464 | 0.84 | KMT2A (0.53) | KMT2AMEN1L3MBTL1ALDH1A1GAA | |
| SCHEMBL3708123 | 0.81 | L3MBTL1 (0.53) | KMT2AMEN1L3MBTL1ACHEALDH1A1 | |
| SCHEMBL23384670 | 0.81 | KMT2A (0.71) | KMT2AMEN1L3MBTL1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105153194-A | Monoamine-monophenol type quinoxalinylbenzoxazin and preparation method thereof | UNIV HARBIN ENG | 2015-12-16 | — | — | CN | disclosed |