SCHEMBL28044927

SCHEMBL28044927

O=S(=O)(O)c1ccccc1S(=O)(=O)NF

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.40
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TTR P02766 2/20 0.39
FABP4 P15090 1/20 0.39
CCNA2 P20248 1/20 0.39
CDK2 P24941 1/20 0.39
MAPK14 Q16539 1/20 0.39
NR4A1 P22736 1/20 0.38
CA1 P00915 3/20 0.37
CA2 P00918 3/20 0.37
MMP1 P03956 3/20 0.37
MMP2 P08253 3/20 0.37
MMP9 P14780 3/20 0.37
MMP8 P22894 3/20 0.37
MMP13 P45452 3/20 0.37
CHAT P28329 1/20 0.36
SNCA P37840 1/20 0.36
KAT6A Q92794 2/20 0.35
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL150335 0.81 TSHR (0.55) MYCTSHRSMN1; SMN2TTRFABP4
SCHEMBL29664068 0.81 TSHR (0.55) MYCTSHRSMN1; SMN2TTRFABP4
SCHEMBL10699531 0.80 CA1 (0.57) MYCTSHRSMN1; SMN2TTRFABP4
SCHEMBL1224131 0.78 CA2 (0.50) CA1CA2CA12CA9
SCHEMBL2972939 0.78 TSHR (0.52) MYCTSHRSMN1; SMN2TTRFABP4
Potassium SCHEMBL999033 0.78 TSHR (0.52) MYCTSHRSMN1; SMN2TTRFABP4
SCHEMBL10627282 0.78 MYC (0.56) MYCTSHRSMN1; SMN2TTRFABP4
SCHEMBL2291963 0.78 TSHR (0.52) MYCTSHRSMN1; SMN2TTRFABP4
SCHEMBL6678754 0.78 TSHR (0.52) MYCTSHRSMN1; SMN2TTRFABP4
Hydrochloric Acid SCHEMBL627715 0.78 TSHR (0.52) MYCTSHRSMN1; SMN2TTRFABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105503976-A Solithromycin intermediate ZHEJIANG JINGXIN PHARMACEUTICAL CO LTD 2016-04-20 CN claimed
CN-105348341-A Method for preparing solithromycin ZHEJIANG JINGXIN PHARMACEUTICAL CO LTD 2016-02-24 CN claimed
CN-105503976-A Solithromycin intermediate ZHEJIANG JINGXIN PHARMACEUTICAL CO LTD 2016-04-20 CN disclosed
CN-105348341-A Method for preparing solithromycin ZHEJIANG JINGXIN PHARMACEUTICAL CO LTD 2016-02-24 CN disclosed