SCHEMBL1224131

SCHEMBL1224131

NS(=O)(=O)c1ccccc1S(=O)(=O)NF

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA2 P00918 14/20 0.50
CA1 P00915 12/20 0.50
CA9 Q16790 8/20 0.50
CA6 P23280 3/20 0.50
CA5A P35218 3/20 0.50
CA12 O43570 3/20 0.50
CA4 P22748 2/20 0.50
CA7 P43166 2/20 0.50
CA5B Q9Y2D0 2/20 0.50
CYP2C9 P11712 1/20 0.50
CA14 Q9ULX7 1/20 0.50
PTGES2 Q9H7Z7 4/20 0.45
PTGES O14684 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL202947 0.81 CA2 (0.70) CA2CA1CA9CA6CA5A
SCHEMBL28044927 0.78 MYC (0.40) CA2CA1CA9CA12
SCHEMBL45019 0.78 CA2 (0.55) CA2CA1CA9CA6CA5A
SCHEMBL10749655 0.78 CA2 (0.67) CA2CA1CA9CA6CA5A
SCHEMBL10750176 0.78 CA2 (0.67) CA2CA1CA9CA6CA5A
SCHEMBL10750170 0.78 CA2 (0.67) CA2CA1CA9CA6CA5A
SCHEMBL8779451 0.76 KAT6A (0.51)
SCHEMBL13850926 0.75 CA2 (0.47) CA2CA1CA9CA6CA5A
SCHEMBL20943708 0.75 HTR6 (0.52) CA2CA1CA12CA7
SCHEMBL29488962 0.75 HTR6 (0.52) CA2CA1CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096782-A1 FLUORINATED CANNABINOID COMPOSITIONS AND METHODS THEREOF COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2025-05-08 WO claimed
WO-2022269257-A1 SPIRO-(FLUORENE-9,9'-(THIO)XANTHENES) UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) 2022-12-29 WO claimed
EP-3426654-B1 DIRECT PALLADIUM-CATALYZED AROMATIC FLUORINATION HARVARD COLLEGE (US) 2021-10-20 EP claimed
CN-108610388-B Preparation method of macrolide 浙江京新药业股份有限公司 2020-11-06 CN claimed
US-10597366-B2 Aryl ethers and uses thereof PELOTON THERAPEUTICS, INC. (US) 2020-03-24 US claimed
US-20190119214-A1 ARYL ETHERS AND USES THEREOF PELOTON THERAPEUTICS, INC. 2019-04-25 US claimed
US-20190077797-A1 PROCESSES FOR PREPARING 2-DIHALO RIBOLACTONES EMORY UNIVERSITY 2019-03-14 US claimed
EP-3426654-A1 DIRECT PALLADIUM-CATALYZED AROMATIC FLUORINATION President and Fellows of Harvard College (US) 2019-01-16 EP claimed
WO-2018134343-A1 SYNTHESIS OF PHOSPHORAMIDATES SANDOZ AG (CH) 2018-07-26 WO claimed
US-20170283960-A1 METHOD OF DISCOVERING FLUORO-CONTAINING COMPOUNDS SHANXI CHEMICAL RESEARCH INSTITUTE CO., LTD. (CN) 2017-10-05 US claimed
WO-2017156265-A1 DIRECT PALLADIUM-CATALYZED AROMATIC FLUORINATION PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2017-09-14 WO claimed
WO-2016106161-A1 METHOD OF DISCOVERING FLUORO-CONTAINING COMPOUNDS SHANXI CHEMICAL RESEARCH INSTITUTE CO., LTD. (CN) 2016-06-30 WO claimed
EP-0708087-B1 Method for making a substituted benzene compound ROHM & HAAS (US) 1999-07-28 EP claimed
US-5670691-A REACTION OF 2-SUBSTITUTED BENZENESULFONATE WITH LITHIUM COMPOUND THEN REACTION WITH ELECTROPHILE TO FORM 2,6-DISUBSTITUTED BENZENESULFONATE ROHM AND HAAS COMPANY (US) 1997-09-23 US claimed
EP-0708087-A1 Method for making a substituted benzene compound ROHM AND HAAS COMPANY (US) 1996-04-24 EP claimed
US-12551499-B2 Highly active compounds against COVID-19 Atea Pharmaceuticals, Inc. (US) 2026-02-17 US disclosed
US-12552758-B2 Inhibitors of MLH1 and/or PMS2 for cancer treatment Neophore Limited (GB) 2026-02-17 US disclosed
US-5254732-A N-fluorosulfonimides and their application as fluorinating agents ALLIED-SIGNAL INC. (US) 1993-10-19 US disclosed
EP-0554025-A2 Fluorinated cyclobutyl purines and pyrimidines E.R. SQUIBB & SONS, INC. (US) 1993-08-04 EP disclosed
EP-0526849-A1 Novel substituted N-Fluoropyridiniumsulfonate, intermediates therefor and preparation processes thereof DAIKIN INDUSTRIES, LTD. (JP) 1993-02-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190077797-A1 PROCESSES FOR PREPARING 2-DIHALO RIBOLACTONES DERA, DPYD, DUS2 CA2 3122/4885CA1 2993/4885CA9 2497/4885
US-12552758-B2 Inhibitors of MLH1 and/or PMS2 for cancer treatment MSH2, PMS2, MSH6 CA2 2256/4885CA1 2823/4885CA9 1702/4885
US-12551499-B2 Highly active compounds against COVID-19 PNP, SLC29A2, MTAP CA2 1052/4885CA1 4250/4885CA9 2969/4885
US-20190119214-A1 ARYL ETHERS AND USES THEREOF HIF1AN, EGLN2, VHL CA2 1902/4885CA1 2771/4885CA9 647/4885
US-10597366-B2 Aryl ethers and uses thereof HIF1AN, EGLN2, VHL CA2 1902/4885CA1 2771/4885CA9 647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.