SCHEMBL28045147

SCHEMBL28045147

CO[Si](Cc1ccccc1)(OC)OCCCl

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.32
TP53 P04637 1/20 0.31
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
ATM Q13315 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
TSHR P16473 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32671232 0.85 LTA4H (0.34) LTA4HTP53SIGMAR1ATMTAAR1
SCHEMBL1963876 0.84 TP53 (0.34) TP53NR1H2NR1H3
SCHEMBL2808324 0.84 TAAR1 (0.39) LTA4HATMTAAR1TSHR
SCHEMBL139765 0.83 TDP1 (0.35) ATMTAAR1
SCHEMBL28045056 0.82 ALDH1A1 (0.39) LTA4HTP53ATMTAAR1TSHR
SCHEMBL28045160 0.82 TDP1 (0.38) LTA4HTP53ATMTAAR1TSHR
SCHEMBL20994307 0.82 IDO1 (0.35) LTA4HTP53ATMTAAR1TSHR
SCHEMBL28472798 0.81 LTA4H (0.41) LTA4HSIGMAR1TSHR
SCHEMBL104953 0.80 TP53 (0.42) LTA4HTP53ATMTAAR1TSHR
SCHEMBL19809353 0.80 TP53 (0.37) LTA4HTP53SIGMAR1ATMTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105163853-A Method for manufacturing catalyst for synthesizing cyclic carbonate MARUZEN PETROCHEM CO LTD 2015-12-16 CN disclosed
CN-105163854-A Method for producing catalyst for synthesizing cyclic carbonate NAT INST OF ADVANCED IND SCIEN 2015-12-16 CN disclosed
CN-105121013-A Method for producing catalyst for cyclic carbonate synthesis MARUZEN PETROCHEM CO LTD 2015-12-02 CN disclosed