SCHEMBL28045159

SCHEMBL28045159

CCCO[Si](OCCC)(OCCC)c1ccccc1CBr

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.30
ELANE P08246 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28045163 0.85 ELANE (0.34) LMNAELANE
SCHEMBL430189 0.82 ALDH1A1 (0.38) ALDH1A1LMNAMEN1KMT2A
SCHEMBL8371242 0.82 NR1I2 (0.33) ALDH1A1LMNAMEN1KMT2A
SCHEMBL1225480 0.82 NR1I2 (0.33) ALDH1A1LMNAMEN1KMT2A
SCHEMBL30504300 0.78 ALDH1A1 (0.36) ALDH1A1
SCHEMBL1225016 0.78 ALDH1A1 (0.36) ALDH1A1
SCHEMBL28045154 0.78 HTR7 (0.33) ALDH1A1LMNAMEN1KMT2A
SCHEMBL4844480 0.77 ALDH1A1 (0.31) ALDH1A1
SCHEMBL21060569 0.77 KDM4E (0.32) ALDH1A1LMNA
SCHEMBL106489 0.76 TSHR (0.35) ALDH1A1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105163853-B The manufacturing method of cyclic carbonate catalyst for synthesizing 丸善石油化学株式会社 2018-06-12 CN disclosed
CN-105121013-B The manufacture method of cyclic carbonate catalyst for synthesizing 丸善石油化学株式会社 2017-10-20 CN disclosed
CN-105163853-A Method for manufacturing catalyst for synthesizing cyclic carbonate MARUZEN PETROCHEM CO LTD 2015-12-16 CN disclosed
CN-105163854-A Method for producing catalyst for synthesizing cyclic carbonate NAT INST OF ADVANCED IND SCIEN 2015-12-16 CN disclosed
CN-105121013-A Method for producing catalyst for cyclic carbonate synthesis MARUZEN PETROCHEM CO LTD 2015-12-02 CN disclosed