Oxalic Acid

Oxalic Acid

SCHEMBL28045245

Cl.Cl.O=C(O)C(=O)O.c1ccncc1.c1ccncc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1SLC6A4

The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 4/20 0.60
TSHR P16473 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ALDH1A1 P00352 2/20 0.39
APP P05067 1/20 0.39
GAA P10253 1/20 0.39
HCAR3 P49019 1/20 0.39
HCAR2 Q8TDS4 1/20 0.39
PLOD2 O00469 2/20 0.36
TAAR1 Q96RJ0 1/20 0.36
PLOD3 O60568 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
HPGD P15428 1/20 0.36
CYP2C19 P33261 1/20 0.36
PLOD1 Q02809 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxalic Acid SCHEMBL28045246 1.00 NAPRT (0.60) NAPRTTSHRTDP1MEN1KMT2A
Oxalic Acid SCHEMBL5874777 0.97 NAPRT (0.64) NAPRTTSHRTDP1MEN1KMT2A
Oxalic Acid SCHEMBL4224676 0.97 NAPRT (0.64) NAPRTTSHRTDP1MEN1KMT2A
Pyridine SCHEMBL11080572 0.90 NAPRT (0.64) NAPRTTSHRTDP1MEN1KMT2A
Pyridine SCHEMBL5875149 0.86 NAPRT (0.69) NAPRTTSHRTDP1MEN1KMT2A
Pyridine SCHEMBL5278800 0.86 NAPRT (0.69) NAPRTTSHRTDP1MEN1KMT2A
Pyridine SCHEMBL910099 0.86 NAPRT (0.69) NAPRTTSHRTDP1MEN1KMT2A
Pyridine SCHEMBL9073450 0.84 NAPRT (0.56) NAPRTTSHRTDP1MEN1KMT2A
Pyridine SCHEMBL28762998 0.84 NAPRT (0.56) NAPRTTSHRTDP1MEN1KMT2A
Pyridine SCHEMBL29133271 0.84 NAPRT (0.56) NAPRTTSHRTDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105165823-A Enhanced Retention Capabilities Through Methods Comprising Surface Treatment Of Functional Particulate Carrier Materials, And Functional Particulate Carrier Materials Made Therefrom WORLD MINERALS INC 2015-12-23 CN disclosed