Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 1/20 | 0.51 |
| ▸ | CETP | P11597 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9184890 | 0.92 | CETP (0.52) | DEGS1CETPMEN1KMT2ATHRB | |
| Hydrochloric Acid SCHEMBL9720712 | 0.92 | MEN1 (0.50) | DEGS1CETPMEN1KMT2ATHRB | |
| SCHEMBL2183193 | 0.91 | MEN1 (0.51) | DEGS1CETPMEN1KMT2ATHRB | |
| SCHEMBL1977485 | 0.91 | MEN1 (0.51) | DEGS1CETPMEN1KMT2ATHRB | |
| Hydrochloric Acid SCHEMBL3973775 | 0.90 | DEGS1 (0.54) | DEGS1CETPMEN1KMT2ATRPV1 | |
| Ammonia Solution, Strong SCHEMBL2175765 | 0.90 | MEN1 (0.50) | DEGS1CETPMEN1KMT2ATHRB | |
| Phosphoric Acid SCHEMBL28871543 | 0.86 | MEN1 (0.46) | MEN1KMT2AFAAH | |
| Phosphoric Acid SCHEMBL10488978 | 0.86 | PLA2G1B (0.46) | MEN1KMT2AMAPTBLMFAAH | |
| Hydrochloric Acid SCHEMBL25267066 | 0.85 | FAAH (0.53) | DEGS1CETPMEN1KMT2ATHRB | |
| Hydrochloric Acid SCHEMBL7586220 | 0.85 | FAAH (0.53) | DEGS1CETPMEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103442567-B | Containing the composition of polymerization plasma type compound comprising imidazole group | BASF SE (DE) | 2016-02-10 | — | — | CN | disclosed |