Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 3/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27785798 | 0.78 | APP (0.48) | MAPT | |
| SCHEMBL27413353 | 0.76 | HCAR2 (0.41) | HCAR2 | |
| SCHEMBL28163549 | 0.74 | DAO (0.41) | MAPTDAORETKDRHCAR2 | |
| SCHEMBL28013856 | 0.74 | MAPT (0.48) | MAPTRETKDRALPL | |
| SCHEMBL2094074 | 0.73 | TAAR1 (0.45) | ALDH1A1MAOBMAOA | |
| SCHEMBL27515285 | 0.73 | HCAR2 (0.39) | HCAR2 | |
| SCHEMBL27657741 | 0.71 | HCAR2 (0.44) | HCAR2 | |
| SCHEMBL27864520 | 0.71 | HCAR2 (0.43) | HCAR2ALDH1A1HPGD | |
| SCHEMBL23929231 | 0.70 | HTR2A (0.40) | MAPTDAORETKDRHCAR2 | |
| SCHEMBL28035629 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105121432-A | Heterocyclic amides as kinase inhibitors | GLAXOSMITHKLINE IP DEV LTD | 2015-12-02 | — | — | CN | disclosed |