Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23929224 | 0.83 | KCNH2 (0.44) | KCNH2DAOGPR84HCAR2ALDH1A1 | |
| SCHEMBL14719236 | 0.75 | DAO (0.57) | DAOMAPTGPR84PTGS1PTGS2 | |
| SCHEMBL20897252 | 0.75 | CA12 (0.55) | DAOHCAR2 | |
| SCHEMBL24622020 | 0.74 | PTGS1 (0.40) | HTR2AKCNH2HTR2CDAOTAAR1 | |
| SCHEMBL28045657 | 0.70 | MAPT (0.39) | DAOMAPTRETKDRHCAR2 | |
| SCHEMBL14814661 | 0.69 | CA12 (0.56) | MAPTRETKDR | |
| SCHEMBL20897239 | 0.69 | ALPL (0.47) | DAOMAPTALDH1A1 | |
| SCHEMBL28236736 | 0.68 | HCAR2 (0.41) | DAOHCAR2 | |
| SCHEMBL7437052 | 0.67 | TAAR1 (0.68) | DAOTAAR1PTGS1PTGS2 | |
| SCHEMBL16232008 | 0.67 | DAO (0.51) | DAOMAPTGPR84RETKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4139275-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | Syneurx International (Taiwan) Corp. (TW) | 2023-03-01 | — | — | EP | disclosed |
| WO-2021213500-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (CN) | 2021-10-28 | — | — | WO | disclosed |