Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.83 |
| ▸ | GAA | P10253 | 1/20 | 0.83 |
| ▸ | FAAH | O00519 | 2/20 | 0.70 |
| ▸ | AANAT | Q16613 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.61 |
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28454170 | 0.89 | GAA (0.77) | MAPTGAAFAAHAANATKMT2A | |
| SCHEMBL9116077 | 0.85 | MAPT (0.71) | MAPTGAAFAAHAANATKMT2A | |
| SCHEMBL7843769 | 0.83 | GFER (0.63) | MAPTGAAFAAHAANATKMT2A | |
| SCHEMBL6703004 | 0.83 | AANAT (0.75) | MAPTGAAFAAHAANATKMT2A | |
| SCHEMBL4856104 | 0.82 | FAAH (1.00) | MAPTFAAHAANATKMT2AMEN1 | |
| SCHEMBL5903804 | 0.81 | AANAT (0.77) | FAAHAANATKMT2AMEN1NPC1 | |
| SCHEMBL10069200 | 0.81 | AANAT (0.77) | AANATKMT2AMEN1NPC1RAB9A | |
| SCHEMBL7677886 | 0.81 | MEN1 (0.84) | MAPTGAAAANATKMT2AMEN1 | |
| SCHEMBL6394942 | 0.81 | MEN1 (0.76) | MAPTFAAHAANATKMT2AMEN1 | |
| SCHEMBL5659833 | 0.81 | MAPT (0.60) | MAPTGAAFAAHAANATKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105198786-A | Aryl-substituted amide compound, preparing method thereof, medicine composition comprising same, and application thereof | INST MED BIOTECHNOLOGY CAMS | 2015-12-30 | — | — | CN | claimed |
| CN-105198786-A | Aryl-substituted amide compound, preparing method thereof, medicine composition comprising same, and application thereof | INST MED BIOTECHNOLOGY CAMS | 2015-12-30 | — | — | CN | disclosed |