Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
| ▸ | FNTA | P49354 | 4/20 | 0.53 |
| ▸ | FNTB | P49356 | 4/20 | 0.53 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28045744 | 1.00 | LTA4H (0.57) | LTA4HFNTAFNTBPGGT1BNPSR1 | |
| SCHEMBL2325127 | 0.87 | LTA4H (0.56) | LTA4HFNTAFNTBPGGT1B | |
| SCHEMBL4956329 | 0.87 | LTA4H (0.56) | LTA4HFNTAFNTBPGGT1BNPSR1 | |
| SCHEMBL2325133 | 0.87 | LTA4H (0.56) | LTA4HFNTAFNTBPGGT1B | |
| SCHEMBL2330911 | 0.85 | LTA4H (0.54) | LTA4HFNTAFNTBPGGT1BNPSR1 | |
| SCHEMBL2330908 | 0.85 | LTA4H (0.54) | LTA4HFNTAFNTBPGGT1BNPSR1 | |
| SCHEMBL6787370 | 0.81 | MME (0.66) | — | |
| SCHEMBL9830037 | 0.80 | MME (0.62) | — | |
| SCHEMBL10585922 | 0.79 | LTA4H (0.54) | LTA4HFNTAFNTBPGGT1BNPSR1 | |
| SCHEMBL5313786 | 0.79 | NPY1R (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175418-A | Pentacyclic indole quinolizine inhibiting cell autophagy, synthesis, antitumor activity and application thereof | UNIV CAPITAL MEDICAL SCIENCES | 2015-12-23 | — | — | CN | disclosed |