Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 2/20 | 0.60 |
| ▸ | AURKA | O14965 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29796528 | 0.79 | MAPK10 (0.73) | MAPK10AURKAKMT2AMEN1MAPT | |
| SCHEMBL7341519 | 0.79 | MAPK10 (0.73) | MAPK10AURKAKMT2AMEN1MAPT | |
| SCHEMBL6662458 | 0.79 | KDM4E (0.63) | MAPK10AURKAKMT2AMEN1GFER | |
| SCHEMBL10094592 | 0.79 | MAPK10 (0.60) | MAPK10KMT2AMEN1GFERKDR | |
| SCHEMBL27420834 | 0.76 | SMN1; SMN2 (0.55) | MAPK10KMT2AMEN1MAPTGFER | |
| SCHEMBL27998656 | 0.75 | MAPK10 (0.56) | MAPK10AURKAKMT2AMEN1MAPT | |
| SCHEMBL1518965 | 0.75 | MAPK10 (1.00) | MAPK10AURKAKMT2AMEN1MAPT | |
| SCHEMBL30754775 | 0.75 | MAPT (0.58) | MAPK10AURKAMAPTKDRALDH1A1 | |
| SCHEMBL10094184 | 0.75 | HPGD (0.48) | MAPK10KMT2AMEN1GFERKDR | |
| SCHEMBL4313791 | 0.75 | KDM4E (0.44) | MAPK10KMT2AMEN1GFERKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102762582-B | Metal complexes comprising diazabenzimidazole carbene ligands and their use in OLEDs | BASF SE (DE) | 2015-11-25 | — | — | CN | disclosed |