Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | APEX1 | P27695 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27926524 | 0.90 | RIPK1 (0.53) | RIPK1CYP19A1MEN1KMT2AMAPT | |
| SCHEMBL27661012 | 0.89 | RIPK1 (0.52) | RIPK1CYP19A1MEN1KMT2AMAPT | |
| SCHEMBL28796148 | 0.85 | CYP19A1 (0.42) | RIPK1CYP19A1MEN1KMT2AMAPT | |
| SCHEMBL27957133 | 0.83 | RIPK1 (0.45) | RIPK1CYP19A1MEN1KMT2AMAPT | |
| SCHEMBL27767398 | 0.83 | RIPK1 (0.45) | RIPK1MEN1KMT2AMAPTGAA | |
| SCHEMBL27957100 | 0.83 | RIPK1 (0.45) | RIPK1MEN1KMT2AMAPTGAA | |
| SCHEMBL29500460 | 0.82 | RIPK1 (0.53) | RIPK1MEN1KMT2AMAPTGAA | |
| SCHEMBL27681022 | 0.81 | RIPK1 (0.46) | RIPK1MEN1KMT2AMAPTGAA | |
| SCHEMBL28500347 | 0.79 | RIPK1 (0.47) | RIPK1CYP19A1MEN1KMT2AMAPT | |
| SCHEMBL663481 | 0.79 | RIPK1 (0.44) | RIPK1CYP19A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115068491-A | Medical application of andrographolide as LTB4 receptor inhibitor | 中国医学科学院药物研究所 | 2022-09-20 | — | — | CN | disclosed |
| CN-115068467-A | Medical application of andrographolide as LTB4 receptor inhibitor | 中国医学科学院药物研究所 | 2022-09-20 | — | — | CN | disclosed |
| CN-105311335-A | Traditional Chinese medicine composition for assisting tumor chemoradiotherapy | LU ZHONGXIN | 2016-02-10 | — | — | CN | disclosed |
| CN-101342254-A | Combination of traditional Chinese medicine extract for preventing and treating atherosis, hyperlipemia, and preparation thereof | TRADITIONAL CHINESE MEDICINE I (CN) | 2009-01-14 | — | — | CN | disclosed |
| CN-101342237-A | Traditional Chinese medicine extract combination for preventing and treating atherosis and preparation thereof | TRADITIONAL CHINESE MEDICINE I (CN) | 2009-01-14 | — | — | CN | disclosed |