Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28841491 | 0.91 | RIPK1 (0.40) | CYP19A1RIPK1NPC1RAB9AMITF | |
| SCHEMBL28862097 | 0.88 | CYP19A1 (0.40) | CYP19A1ACHEPLK1BACE1RIPK1 | |
| SCHEMBL28045819 | 0.85 | RIPK1 (0.51) | CYP19A1ACHEPLK1BACE1RIPK1 | |
| SCHEMBL28571818 | 0.78 | L3MBTL1 (0.35) | CYP19A1RIPK1NPC1RAB9AGAA | |
| SCHEMBL27442244 | 0.78 | RIPK1 (0.59) | CYP19A1RIPK1NPC1RAB9AMITF | |
| SCHEMBL27926524 | 0.75 | RIPK1 (0.53) | CYP19A1RIPK1NPC1RAB9AGAA | |
| SCHEMBL27715699 | 0.74 | CYP19A1 (0.38) | CYP19A1ACHEPLK1BACE1MGAM | |
| SCHEMBL27661012 | 0.74 | RIPK1 (0.52) | CYP19A1RIPK1NPC1RAB9AGAA | |
| SCHEMBL29169312 | 0.72 | ALDH1A1 (0.35) | CYP19A1RIPK1NPC1RAB9AMITF | |
| SCHEMBL29500460 | 0.70 | RIPK1 (0.53) | RIPK1NPC1RAB9AMITFNR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102552193-A | Andrographolide tablet and preparation method thereof | TIANSHENG PHARMACEUTICAL GROUP CO LTD | 2012-07-11 | — | — | CN | disclosed |