Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | MMP17 | Q9ULZ9 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28175071 | 0.84 | SRD5A2 (0.40) | MMP2MMP3MMP9MMP13ADAM17 | |
| SCHEMBL27594084 | 0.81 | NPSR1 (0.39) | SMN1; SMN2MMP2MMP3MMP9MMP13 | |
| SCHEMBL3642719 | 0.81 | GRM5 (0.47) | ABCB1BACE1KDM4E | |
| SCHEMBL27552573 | 0.80 | PROKR1 (0.40) | PPARAALDH1A1GAAMAPT | |
| SCHEMBL28045806 | 0.79 | OGA (0.47) | LMNAKDM4EALDH1A1MAPT | |
| SCHEMBL28056789 | 0.79 | HDAC1 (0.34) | BACE1 | |
| SCHEMBL27785450 | 0.78 | KDM4E (0.48) | L3MBTL1MMP3MMP13AKR1B1KDM4E | |
| SCHEMBL28045832 | 0.78 | ACHE (0.39) | LMNASMN1; SMN2MMP2MMP3MMP9 | |
| SCHEMBL27512006 | 0.77 | OGA (0.46) | SMN1; SMN2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL31611716 | 0.72 | HDAC1 (0.45) | PPARAAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143222-A | Glycosidase inhibitors | MERCK PATENT GMBH | 2015-12-09 | — | — | CN | disclosed |