Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27552573 | 0.83 | PROKR1 (0.40) | — | |
| SCHEMBL16321867 | 0.81 | ESR2 (0.44) | — | |
| SCHEMBL15536669 | 0.80 | PROKR1 (0.32) | HDAC1 | |
| SCHEMBL28045841 | 0.79 | LMNA (0.38) | BACE1 | |
| SCHEMBL28175071 | 0.77 | SRD5A2 (0.40) | BACE1 | |
| SCHEMBL27594084 | 0.77 | NPSR1 (0.39) | — | |
| SCHEMBL28045806 | 0.77 | OGA (0.47) | — | |
| SCHEMBL15536839 | 0.76 | SRD5A2 (0.40) | HDAC1 | |
| SCHEMBL27512006 | 0.75 | OGA (0.46) | — | |
| SCHEMBL28087020 | 0.72 | CCR3 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104520292-B | Sulphonylpiperidine derivant and they are for treating the purposes of disease of front dynein mediation | 武田药品工业株式会社 | 2016-09-14 | — | — | CN | disclosed |
| CN-105324372-A | 1-sulfonylpiperidine derivatives as prokineticin receptor modulators | TAKEDA PHARMACEUTICAL | 2016-02-10 | — | — | CN | disclosed |