Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.52 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.42 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.42 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.42 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 3/20 | 0.41 |
| ▸ | RXRB | P28702 | 3/20 | 0.41 |
| ▸ | RXRG | P48443 | 3/20 | 0.41 |
| ▸ | RARB | P10826 | 2/20 | 0.41 |
| ▸ | RARG | P13631 | 2/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16742742 | 0.82 | FFAR2 (0.41) | HCAR2PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL2406424 | 0.82 | HCAR2 (0.53) | HCAR2PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL23422044 | 0.76 | FFAR2 (0.38) | HCAR2PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL1912543 | 0.74 | CDC7 (0.57) | ALDH1A1KDM4EGAAMAPTRAB9A | |
| SCHEMBL11667574 | 0.72 | HCAR2 (0.47) | HCAR2PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL1810308 | 0.72 | HCAR2 (0.61) | HCAR2PRKAB2PRKAG1PRKAA2PRKAA1 | |
| Formaldehyde SCHEMBL27847261 | 0.71 | HCAR2 (0.55) | HCAR2RXRARXRBRXRGALDH1A1 | |
| SCHEMBL2408239 | 0.70 | HCAR2 (0.41) | HCAR2PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL2408241 | 0.70 | HCAR2 (0.41) | HCAR2PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL16198634 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143222-B | Glycosidase inhibitor | 默克专利有限公司 | 2018-02-02 | — | — | CN | disclosed |
| CN-105143222-A | Glycosidase inhibitors | MERCK PATENT GMBH | 2015-12-09 | — | — | CN | disclosed |