Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 10/20 | 0.39 |
| ▸ | TSPO | P30536 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 2/20 | 0.38 |
| ▸ | TLR4 | O00206 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17443302 | 0.77 | HDAC4 (0.46) | MEN1KMT2ACA2 | |
| SCHEMBL27830678 | 0.75 | ACLY (0.48) | KMT2AACLY | |
| SCHEMBL14830605 | 0.75 | MRGPRX1 (0.48) | MRGPRX1TSPOKMT2ABRAFHRH1 | |
| SCHEMBL15847815 | 0.75 | ACLY (0.51) | MRGPRX1TSPOMEN1KMT2ABRAF | |
| SCHEMBL15847427 | 0.75 | ACLY (0.54) | MRGPRX1TSPOBRAFTLR4ACLY | |
| SCHEMBL17465678 | 0.74 | ACLY (0.41) | MRGPRX1TSPOKMT2ABRAFTLR4 | |
| SCHEMBL3336145 | 0.72 | BRAF (0.38) | MRGPRX1TSPOBRAFTLR4HRH1 | |
| SCHEMBL17443300 | 0.72 | MRGPRX1 (0.51) | MRGPRX1TSPOACLY | |
| SCHEMBL6490089 | 0.71 | BRAF (0.44) | MEN1KMT2ABRAFCA2KDM1A | |
| SCHEMBL28065646 | 0.71 | MEN1 (0.43) | MEN1KMT2AMAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209031-A | Novel antiviral agents against HBV infection | UNIV DREXEL | 2015-12-30 | — | — | CN | disclosed |