Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | FERMT2 | Q96AC1 | 2/20 | 0.35 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28334498 | 0.80 | CDK2 (0.45) | MAPTIDO1FLT1 | |
| SCHEMBL5265818 | 0.75 | MEN1 (0.57) | MEN1KMT2ANPC1RAB9ANPSR1 | |
| SCHEMBL30063441 | 0.75 | MEN1 (0.57) | MEN1KMT2ANPC1RAB9ANPSR1 | |
| SCHEMBL28136523 | 0.74 | KDM6B (0.40) | MEN1KMT2ANPSR1KDM4CHDAC1 | |
| SCHEMBL28279536 | 0.73 | MEN1 (0.47) | MEN1KMT2AKIF11 | |
| SCHEMBL16702566 | 0.73 | KDM4E (0.47) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL28065647 | 0.72 | MEN1 (0.40) | MEN1KMT2ANPC1RAB9ANPSR1 | |
| SCHEMBL27602806 | 0.72 | KMT2A (0.53) | MEN1KMT2ANPC1RAB9ANPSR1 | |
| SCHEMBL29250971 | 0.72 | MEN1 (0.53) | MEN1KMT2ANPC1RAB9AKIF11 | |
| SCHEMBL27653420 | 0.71 | MEN1 (0.48) | MEN1KMT2AKIF11IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105682656-B | Compositions and methods for modulating farnesoid X receptors | 诺华股份有限公司 | 2019-11-05 | — | — | CN | disclosed |
| CN-105682656-A | Compositions and methods for modulating farnesoid x receptors | 诺华股份有限公司 | 2016-06-15 | — | — | CN | disclosed |