SCHEMBL28045982

SCHEMBL28045982

COc1ccc(Cl)c(OC)c1NC(=O)CC(C)=O

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.56
MEN1 O00255 4/20 0.56
ALDH1A1 P00352 4/20 0.56
PDE4D Q08499 1/20 0.42
KDM4E B2RXH2 1/20 0.41
HSD17B10 Q99714 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
MAPT P10636 1/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
HPGD P15428 2/20 0.39
TP53 P04637 1/20 0.39
PKM P14618 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
LMNA P02545 1/20 0.39
USP2 O75604 1/20 0.39
TSHR P16473 1/20 0.39
TAS1R3 Q7RTX0 1/20 0.39
TAS1R1 Q7RTX1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28045983 0.88 MEN1 (0.56) KMT2AMEN1ALDH1A1PDE4DSMN1; SMN2
SCHEMBL11705582 0.88 MEN1 (0.58) KMT2AMEN1ALDH1A1SMN1; SMN2MAPT
SCHEMBL28045985 0.83 MEN1 (0.60) KMT2AMEN1ALDH1A1PDE4DSMN1; SMN2
SCHEMBL7133200 0.79 ALDH1A1 (0.55) KMT2AMEN1ALDH1A1KDM4EHSD17B10
SCHEMBL28045984 0.78 MEN1 (0.53) KMT2AMEN1ALDH1A1KDM4EMAPT
SCHEMBL28045924 0.77 MEN1 (0.63) KMT2AMEN1ALDH1A1SMN1; SMN2HTT
SCHEMBL7603112 0.75 KMT2A (0.54) KMT2AMEN1ALDH1A1KDM4EHPGD
SCHEMBL14492204 0.75 ALDH1A1 (0.65) KMT2AMEN1ALDH1A1SMN1; SMN2MAPT
SCHEMBL28045991 0.73 MEN1 (0.52) KMT2AMEN1ALDH1A1MAPTTDP1
SCHEMBL6782568 0.72 PDE4D (0.49) KMT2AALDH1A1PDE4DKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105143353-B Disazo pigment composition and method for producing same 东洋油墨SC控股株式会社 2017-03-15 CN disclosed
CN-105143353-A Disazo pigment composition and method for producing same TOYO INK SC HOLDINGS CO LTD 2015-12-09 CN disclosed