Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | RAF1 | P04049 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2013991 | 0.92 | KMT2A (0.62) | KMT2AMEN1ALDH1A1RAF1POLB | |
| SCHEMBL13580638 | 0.89 | ALDH1A1 (0.53) | KMT2AMEN1ALDH1A1POLBLMNA | |
| SCHEMBL7133200 | 0.86 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1POLBKDM4E | |
| SCHEMBL31365394 | 0.82 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1POLBKDM4E | |
| SCHEMBL17509893 | 0.82 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1POLBKDM4E | |
| SCHEMBL2088329 | 0.81 | RAF1 (0.53) | KMT2AMEN1ALDH1A1RAF1KDM4E | |
| SCHEMBL2088326 | 0.81 | RAF1 (0.53) | KMT2AMEN1ALDH1A1RAF1POLB | |
| SCHEMBL12720508 | 0.81 | MEN1 (0.80) | KMT2AMEN1ALDH1A1POLBKDM4E | |
| SCHEMBL2093882 | 0.81 | RAF1 (0.53) | KMT2AMEN1ALDH1A1RAF1POLB | |
| SCHEMBL300285 | 0.80 | KMT2A (0.66) | KMT2AMEN1ALDH1A1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124904-B1 | SOLID SOLUTIONS OF MONOAZO PIGMENTS | CIBA SC HOLDING AG (CH) | 2002-12-18 | — | — | EP | disclosed |
| US-6482257-B1 | Solid solutions of monoazo pigments | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-11-19 | — | — | US | disclosed |
| EP-1124904-A1 | SOLID SOLUTIONS OF MONOAZO PIGMENTS | Ciba SC Holding AG (CH) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026303-A1 | SOLID SOLUTIONS OF MONOAZO PIGMENTS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-05-11 | — | — | WO | disclosed |