SCHEMBL28046155

SCHEMBL28046155

CCc1cccc(CN)c1NC(=S)NN

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.59
MAPT P10636 4/20 0.59
GAA P10253 3/20 0.59
HTT P42858 2/20 0.51
PKM P14618 1/20 0.46
ALOX12 P18054 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
KDM4E B2RXH2 2/20 0.43
CACNA1C Q13936 1/20 0.43
SCN5A Q14524 1/20 0.43
MEN1 O00255 2/20 0.41
LMNA P02545 2/20 0.41
KMT2A Q03164 2/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
CYP2C19 P33261 1/20 0.41
HIF1A Q16665 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8514556 0.93 ALDH1A1 (0.67) ALDH1A1MAPTGAAHTTPKM
SCHEMBL16401841 0.84 ALDH1A1 (0.63) ALDH1A1MAPTGAAHTTALOX12
SCHEMBL28222224 0.83 HTT (0.50) ALDH1A1MAPTGAAHTTPKM
SCHEMBL28047579 0.83 CACNA1C (0.49) ALDH1A1MAPTGAAHTTPKM
SCHEMBL30013382 0.82 HTT (0.63) ALDH1A1MAPTGAAHTTPKM
SCHEMBL28135897 0.79 ALDH1A1 (0.53) ALDH1A1MAPTGAAHTTALOX12
SCHEMBL27877981 0.78 CACNA1C (0.50) ALDH1A1MAPTHTTKDM4ECACNA1C
SCHEMBL11513958 0.78 HTT (0.58) ALDH1A1MAPTGAAHTTPKM
SCHEMBL11541523 0.76 ALDH1A1 (0.57) ALDH1A1MAPTGAAHTTPKM
SCHEMBL11543470 0.75 CACNA1C (0.54) ALDH1A1MAPTGAAHTTPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105531265-B Pesticidal compounds 巴斯夫欧洲公司 2018-07-20 CN disclosed
CN-105531265-A Pesticidal compounds BASF SE 2016-04-27 CN disclosed