SCHEMBL28047579

SCHEMBL28047579

CCc1cccc(CN)c1NC(N)=S

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CACNA1C Q13936 2/20 0.49
SCN5A Q14524 2/20 0.49
HTT P42858 3/20 0.47
ALDH1A1 P00352 4/20 0.45
KDM4E B2RXH2 1/20 0.45
CYP2C19 P33261 2/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
HIF1A Q16665 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MAPT P10636 3/20 0.42
GAA P10253 2/20 0.42
LMNA P02545 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
NLRP3 Q96P20 1/20 0.42
PKM P14618 1/20 0.42
ALOX12 P18054 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11543470 0.93 CACNA1C (0.54) CACNA1CSCN5AHTTALDH1A1KDM4E
SCHEMBL28222224 0.86 HTT (0.50) CACNA1CSCN5AHTTALDH1A1KDM4E
SCHEMBL28046155 0.83 ALDH1A1 (0.59) CACNA1CSCN5AHTTALDH1A1KDM4E
SCHEMBL5520049 0.83 ALDH1A1 (0.58) HTTALDH1A1KDM4EALOX15TDP1
SCHEMBL27877981 0.81 CACNA1C (0.50) CACNA1CSCN5AHTTALDH1A1KDM4E
SCHEMBL5538230 0.79 HTT (0.50) CACNA1CSCN5AHTTTDP1LMNA
SCHEMBL28135897 0.78 ALDH1A1 (0.53) HTTALDH1A1KDM4ECYP2C19MAPT
SCHEMBL30013382 0.77 HTT (0.63) CACNA1CSCN5AHTTALDH1A1KDM4E
SCHEMBL11060045 0.77 HTT (0.51) CACNA1CSCN5AHTTALDH1A1KDM4E
SCHEMBL27877978 0.77 SMN1; SMN2 (0.51) CACNA1CSCN5AHTTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106572658-B Molecule and relative intermediate, composition and method with certain disinsection efficiencies 美国陶氏益农公司 2019-11-08 CN disclosed
CN-108369222-A Opioid receptor modulators and uses thereof 明尼苏达大学董事会 2018-08-03 CN disclosed
CN-107573295-A Molecule and intermediate, composition and its correlation technique with certain agricultural chemicals effectiveness 美国陶氏益农公司 2018-01-12 CN disclosed
CN-105209450-B Molecules and intermediates having pesticidal utility, compositions and methods relating thereto 美国陶氏益农公司 2017-10-20 CN disclosed
CN-106572658-A Molecules having certain pesticidal utilities, and intermediates, compositions, and processes related thereto 美国陶氏益农公司 2017-04-19 CN disclosed
CN-105209450-A Molecules and intermediates having pesticidal utility, compositions and methods relating thereto DOW AGROSCIENCES LLC 2015-12-30 CN disclosed