SCHEMBL28046255

SCHEMBL28046255

CS(=O)(=O)Nc1ccc(Nc2ccc(N)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.57
CA2 P00918 2/20 0.57
CA9 Q16790 2/20 0.57
CA12 O43570 1/20 0.57
CHEK1 O14757 1/20 0.54
PRKD3 O94806 1/20 0.54
CDK8 P49336 1/20 0.54
LIMK1 P53667 1/20 0.54
ROCK1 Q13464 1/20 0.54
CLK4 Q9HAZ1 1/20 0.54
DYRK1B Q9Y463 1/20 0.54
KEAP1 Q14145 2/20 0.54
ALDH1A1 P00352 4/20 0.53
HTT P42858 3/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
KDM4E B2RXH2 1/20 0.53
LMNA P02545 1/20 0.53
HPGD P15428 1/20 0.53
MAPT P10636 3/20 0.50
CYP1A2 P05177 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL656210 0.94 CA1 (0.63) CA1CA2CA9CA12KEAP1
Hydrochloric Acid SCHEMBL1530083 0.91 CA1 (0.61) CA1CA2CA9CA12KEAP1
SCHEMBL2497654 0.88 KIF11 (0.66) CA1CA2CA9CA12PRKD3
SCHEMBL9387480 0.86 KEAP1 (0.76) CA1CA2CA9CA12KEAP1
SCHEMBL28119379 0.84 CA1 (0.53) CA1CA2CA9CA12KEAP1
SCHEMBL27516685 0.82 CA1 (0.71) CA1CA2CA9CA12PRKD3
SCHEMBL12054668 0.82 KEAP1 (0.75) CA1CA2CA9CA12KEAP1
SCHEMBL9479898 0.81 KEAP1 (0.83) CA1CA2CA9CA12KEAP1
P-Cresol SCHEMBL11694488 0.78 CA1 (0.50) CA1CA2CA9CA12KEAP1
Sulfuric Acid SCHEMBL475959 0.78 MAPT (0.58) CA1CA2CA9CA12KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105209123-A Dyeing or lightening process using a composition rich in fatty substances comprising an alcohol having at least 20 carbons, compositions and device OREAL 2015-12-30 CN disclosed