Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GLI1 | P08151 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15415262 | 0.90 | — | — | |
| SCHEMBL2736560 | 0.79 | CES2 (0.46) | CES2CES1HDAC8HDAC6GAA | |
| SCHEMBL761357 | 0.77 | CES2 (0.50) | CES2CES1HDAC8HDAC6GAA | |
| Hydrochloric Acid SCHEMBL7367917 | 0.77 | CES2 (0.43) | CES2CES1HDAC8HDAC6GAA | |
| SCHEMBL16938641 | 0.77 | CES2 (0.50) | CES2CES1HDAC8HDAC6GAA | |
| Hydrochloric Acid SCHEMBL390396 | 0.75 | CES2 (0.48) | CES2CES1HDAC8HDAC6GAA | |
| SCHEMBL15217220 | 0.75 | CES2 (0.42) | CES2CES1HDAC8HDAC6GAA | |
| SCHEMBL771433 | 0.75 | RIPK1 (0.41) | CES2CES1HDAC8HDAC6GAA | |
| SCHEMBL4639228 | 0.74 | — | — | |
| SCHEMBL24858527 | 0.73 | CES2 (0.46) | CES2CES1HDAC8HDAC6GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105324366-A | Phenylimidazole derivative and therapeutic or prophylactic agent for inflammatory diseases and the like | NIPPON SODA CO | 2016-02-10 | — | — | CN | disclosed |