Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Imidazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL1936380 | 0.97 | — | — | |
| Imidazole SCHEMBL28360158 | 0.97 | — | — | |
| Imidazole SCHEMBL68016 | 0.97 | — | — | |
| Imidazole SCHEMBL9275612 | 0.97 | ALDH1A1 (0.93) | — | |
| Imidazole SCHEMBL2369283 | 0.97 | ALDH1A1 (0.93) | — | |
| Imidazole SCHEMBL709086 | 0.97 | ALDH1A1 (0.93) | — | |
| Imidazole SCHEMBL15123724 | 0.97 | ALDH1A1 (0.93) | — | |
| Imidazole SCHEMBL113116 | 0.97 | — | — | |
| Imidazole SCHEMBL9275617 | 0.97 | — | — | |
| Imidazole SCHEMBL28098325 | 0.97 | ALDH1A1 (0.93) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105289848-B | A kind of method for floating of fluorite | 浙江工业大学 | 2017-11-07 | — | — | CN | disclosed |
| CN-105289848-A | Fluorite flotation method | UNIV ZHEJIANG TECHNOLOGY | 2016-02-03 | — | — | CN | disclosed |