Imidazole

Imidazole

SCHEMBL2369283

N.c1c[nH]cn1.c1c[nH]cn1

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.93
FKBP5 Q13451 1/20 0.93

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Imidazole SCHEMBL1936380 1.00
Imidazole SCHEMBL113116 1.00
Imidazole SCHEMBL15123724 1.00 ALDH1A1 (0.93) ALDH1A1FKBP5
Imidazole SCHEMBL15813745 0.97
Imidazole SCHEMBL28046402 0.97
Imidazole SCHEMBL28046413 0.97
Imidazole SCHEMBL1445454 0.97
Imidazole SCHEMBL11803881 0.97
Imidazole SCHEMBL28478036 0.97
Imidazole SCHEMBL2684565 0.96 ALDH1A1 (1.00) ALDH1A1FKBP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108654684-B B/L acid modified organic silicon ball catalyst, preparation and application thereof 中国科学院大连化学物理研究所 2020-09-04 CN claimed
CN-106632769-B A kind of preparation method of micron size hybrid polymer microsphere 长春工业大学 2018-11-02 CN claimed
CN-106632769-A A preparing method of micron monodisperse organic/inorganic hybrid polymer microspheres 长春工业大学 2017-05-10 CN claimed
CN-116718656-A Redox polymer enzyme deposition process and preparation method of enzyme electrode 杭州柏医健康科技有限公司 2023-09-08 CN disclosed
CN-115505007-A Sulfobetaine inner salt type hetero-bis-nitrogen heterocyclic carbene palladium complex and synthesis method and application thereof 常州大学 2022-12-23 CN disclosed
CN-108654684-B B/L acid modified organic silicon ball catalyst, preparation and application thereof 中国科学院大连化学物理研究所 2020-09-04 CN disclosed
US-20190169342-A1 POLYIMIDAZOLES FOR USE AS BILE ACID SEQUESTRANTS RELYPSA, INC. 2019-06-06 US disclosed
CN-109135146-A Carrier-free colour special plastic bloom modified master 常州达奥新材料科技有限公司 2019-01-04 CN disclosed
EP-3130343-B1 POLYIMIDAZOLES FOR USE AS BILE ACID SEQUESTRANTS RELYPSA INC (US) 2018-05-09 EP disclosed
CN-104817251-B A kind of composite high-molecular sludge dehydrating agent and preparation method thereof 华南理工大学 2018-01-09 CN disclosed
CN-106198170-B A kind of biological tissue embedding agent and embedding method 华中科技大学 2017-08-18 CN disclosed
CN-106198170-A A kind of biological tissue embedding agent and embedding method 华中科技大学 2016-12-07 CN disclosed
CN-105498834-A Heterogeneous catalyst and application of heterogeneous catalyst in ammoniation reaction of polyhydroxy compound DALIAN INST CHEMICAL PHYSICS CAS 2016-04-20 CN disclosed
CN-105435842-A Homogeneous catalyst and application thereof in polyhydroxy compound ammoniation reaction DALIAN INST CHEMICAL PHYSICS CAS 2016-03-30 CN disclosed
CN-104031076-A Diimidazole nitrogen ligand-controlled 1,3,5-trimesic acid zinc complex and preparation method thereof UNIV HENGYANG NORMAL 2014-09-10 CN disclosed
CN-104031076-A Diimidazole nitrogen ligand-controlled 1,3,5-trimesic acid zinc complex and preparation method thereof UNIV HENGYANG NORMAL 2014-09-10 CN disclosed
US-20130189215-A1 POLYIMIDAZOLES FOR USE AS BILE ACID SEQUESTRANTS RELYPSA, INC. (US) 2013-07-25 US disclosed
EP-2538947-A1 POLYIMIDAZOLES FOR USE AS BILE ACID SEQUESTRANTS Relypsa, Inc. (US) 2013-01-02 EP disclosed
WO-2011106545-A1 POLYIMIDAZOLES FOR USE AS BILE ACID SEQUESTRANTS RELYPSA, INC. (US) 2011-09-01 WO disclosed
CN-1061401-A The preparation method of carboxylic acid anhydride BP CHEM INT LTD (GB) 1992-05-27 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130189215-A1 POLYIMIDAZOLES FOR USE AS BILE ACID SEQUESTRANTS NR1H4, SLC10A2, ITCH ALDH1A1 4043/4885FKBP5 142/4885
US-20190169342-A1 POLYIMIDAZOLES FOR USE AS BILE ACID SEQUESTRANTS NR1H4, SLC10A2, ITCH ALDH1A1 4043/4885FKBP5 142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.