Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 3/20 | 0.33 |
| ▸ | JAK2 | O60674 | 3/20 | 0.33 |
| ▸ | PRKCA | P17252 | 3/20 | 0.33 |
| ▸ | JAK1 | P23458 | 3/20 | 0.33 |
| ▸ | TYK2 | P29597 | 3/20 | 0.33 |
| ▸ | KDR | P35968 | 3/20 | 0.33 |
| ▸ | FLT3 | P36888 | 3/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | PARG | Q86W56 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9939615 | 0.72 | L3MBTL1 (0.61) | L3MBTL1ABL1TBK1KMOPROKR1 | |
| SCHEMBL21405684 | 0.72 | BACE1 (0.42) | ABL1MAPTCYP11B2KMT5BKMT5C | |
| SCHEMBL30532198 | 0.72 | BACE1 (0.42) | ABL1MAPTCYP11B2KMT5BKMT5C | |
| SCHEMBL7707654 | 0.72 | PROKR1 (0.44) | L3MBTL1KMOPROKR1CHRNA7CYP11B2 | |
| SCHEMBL31219695 | 0.71 | CYP17A1 (0.35) | L3MBTL1ABL1AURKAJAK2PRKCA | |
| SCHEMBL28798602 | 0.71 | L3MBTL1 (0.41) | L3MBTL1ABL1TBK1KMOMAPT | |
| SCHEMBL22288137 | 0.70 | L3MBTL1 (0.58) | L3MBTL1ABL1KMOKDM4ECYP11B2 | |
| SCHEMBL30452394 | 0.70 | L3MBTL1 (0.58) | L3MBTL1ABL1KMOKDM4ECYP11B2 | |
| SCHEMBL20623030 | 0.70 | L3MBTL1 (0.58) | L3MBTL1ABL1KMOKDM4ECYP11B2 | |
| SCHEMBL25243084 | 0.68 | L3MBTL1 (0.37) | L3MBTL1KMOPROKR1CYP11B2ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103261167-B | 6 of replacement, 6-condenses nitrogen-containing heterocycle compound and uses thereof | HOFFMAN-LA ROCHE LTD. (CH) | 2016-05-04 | — | — | CN | disclosed |