Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | TACR3 | P29371 | 1/20 | 0.31 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29849457 | 0.80 | MAP3K12 (0.45) | MAPT | |
| SCHEMBL24800367 | 0.73 | ALDH1A1 (0.37) | MAPT | |
| SCHEMBL30772171 | 0.73 | ALDH1A1 (0.37) | MAPT | |
| SCHEMBL29656578 | 0.72 | KDM4E (0.44) | L3MBTL1ABL1NPC1RAB9ATBK1 | |
| SCHEMBL28798701 | 0.72 | KDM4E (0.44) | L3MBTL1ABL1NPC1RAB9ATBK1 | |
| SCHEMBL29656652 | 0.71 | IP6K1 (0.45) | L3MBTL1NPY5RKDM4E | |
| SCHEMBL26296935 | 0.71 | KCNH2 (0.43) | NPY5RPSMB5NPC1RAB9A | |
| SCHEMBL28046484 | 0.71 | L3MBTL1 (0.47) | L3MBTL1ABL1TBK1KMOKDM4E | |
| SCHEMBL24203389 | 0.69 | ALDH1A1 (0.38) | L3MBTL1KDM4EMAPTPDE10A | |
| SCHEMBL16652410 | 0.68 | KDM4E (0.34) | L3MBTL1NPY5RPSMB5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539245-A | Pyrimidine-fused ring derivative-containing regulator, and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2022-05-27 | — | — | CN | disclosed |