Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | MMP12 | P39900 | 1/20 | 0.52 |
| ▸ | MMP14 | P50281 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7166881 | 0.90 | GAA (0.62) | ALDH1A1HTTGAAMEN1KMT2A | |
| SCHEMBL21424287 | 0.80 | MEN1 (0.52) | LMNAHTTMEN1KMT2AL3MBTL1 | |
| SCHEMBL12209182 | 0.77 | LMNA (0.60) | LMNAALDH1A1RAB9AHTTGAA | |
| SCHEMBL639534 | 0.77 | HDAC1 (0.49) | — | |
| SCHEMBL639533 | 0.77 | HDAC1 (0.49) | — | |
| SCHEMBL18134713 | 0.77 | ALDH1A1 (0.56) | LMNAALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL7354606 | 0.77 | MEN1 (0.60) | LMNAALDH1A1HTTMEN1KMT2A | |
| SCHEMBL6635643 | 0.77 | GAA (0.60) | LMNAALDH1A1HTTGAAMEN1 | |
| SCHEMBL8058781 | 0.76 | LMNA (0.57) | LMNAALDH1A1RAB9AHTTGAA | |
| SCHEMBL641514 | 0.75 | FOLH1 (0.46) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104080777-B | Morpholinyl derivatives as MOGAT-2 inhibitors | ELI LILLY AND CO. (US) | 2015-12-09 | — | — | CN | disclosed |