SCHEMBL28046683

SCHEMBL28046683

c1ccc(C(c2ccccc2)(c2ccccc2)c2c[nH]cn2)cc1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 2/20 0.32
TSHR P16473 2/20 0.31
ALDH1A1 P00352 1/20 0.31
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30527947 0.80 ALDH1A1 (0.38) TSHRALDH1A1
SCHEMBL27493049 0.77 MAPK1 (0.32) KCNN4TSHRALDH1A1KMT2A
SCHEMBL9416066 0.77 KDM4E (0.43) ALDH1A1KMT2A
SCHEMBL27529617 0.74 KMT2A (0.35) TSHRALDH1A1KMT2A
SCHEMBL10457289 0.73 KDM4E (0.35) TSHRALDH1A1KMT2A
SCHEMBL28322119 0.73 SLC6A2 (0.39) KCNN4
SCHEMBL10250249 0.73 KMT2A (0.41) KMT2A
SCHEMBL10250228 0.72 MEN1 (0.37) KMT2A
SCHEMBL4790426 0.68 MAPT (0.39) KCNN4TSHRKMT2A
SCHEMBL28918481 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103370808-B organic electroluminescent device 联邦科学和工业研究组织 2016-12-07 CN disclosed
CN-105339355-A Novel CYP17 inhibitor/antiandrogen ORION CORP 2016-02-17 CN disclosed
CN-105111210-A Fused imidazole derivatives useful as IDO inhibitors NEWLINK GENETICKS CORP 2015-12-02 CN disclosed