SCHEMBL28046780

SCHEMBL28046780

C=C(CCCS(=O)(=O)O)C(=O)OCCC.[KH]

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
THRB P10828 1/20 0.32
EPHX2 P34913 1/20 0.31
APP P05067 1/20 0.31
DGKA P23743 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5671965 0.86 APP (0.34) TSHRAPP
SCHEMBL9436660 0.85 TSHR (0.42) TSHRTHRBEPHX2DGKA
SCHEMBL28046711 0.85 TSHR (0.42) TSHRTHRBEPHX2APPDGKA
SCHEMBL5969185 0.85 ALDH1A1 (0.39) TSHRTHRBEPHX2APP
SCHEMBL6049037 0.83 TSHR (0.47) TSHREPHX2DGKA
SCHEMBL11650042 0.81 TSHR (0.37) TSHRTHRB
Methacrylic Acid SCHEMBL22089841 0.81 TSHR (0.39) TSHRTHRB
SCHEMBL3477341 0.81 TSHR (0.50) TSHRTHRBDGKA
SCHEMBL11142420 0.79 TSHR (0.53) TSHRDGKA
SCHEMBL8579449 0.78 ALDH1A1 (0.37) TSHREPHX2APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111249930-B Hydrophilic filter membrane with side chain hydrophilic group and preparation and use methods thereof 恩特格里斯公司 2024-04-05 CN disclosed
CN-113943428-B Conductive gel for electrocardiograph detection and preparation method thereof 郭艳 2023-11-14 CN disclosed
CN-113943428-A Conductive gel for electrocardiographic detection and preparation method thereof 郭艳 2022-01-18 CN disclosed
CN-105153359-A Conductive hydrogel, conductive hydrogel coil and their preparation methods DONGGUAN WANKANG MEDICAL DEVICES CO LTD 2015-12-16 CN disclosed