Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6049037 | 0.94 | TSHR (0.47) | TSHRDGKAALDH1A1CES1CES2 | |
| SCHEMBL11650042 | 0.90 | TSHR (0.37) | TSHRALDH1A1THRB | |
| SCHEMBL28046780 | 0.85 | TSHR (0.38) | TSHRDGKATHRBEPHX2 | |
| SCHEMBL170886 | 0.84 | TSHR (0.52) | TSHRDGKAALDH1A1CES1HPGD | |
| SCHEMBL28046711 | 0.83 | TSHR (0.42) | TSHRDGKAALDH1A1HPGDTHRB | |
| SCHEMBL27843092 | 0.83 | TSHR (0.37) | TSHRDGKAALDH1A1CES1HPGD | |
| SCHEMBL6049055 | 0.82 | THRB (0.36) | TSHRTHRB | |
| SCHEMBL3081526 | 0.82 | TSHR (0.55) | TSHRDGKAALDH1A1CES1HPGD | |
| SCHEMBL5167857 | 0.82 | TSHR (0.60) | TSHRDGKAALDH1A1CES1HPGD | |
| SCHEMBL3477341 | 0.82 | TSHR (0.50) | TSHRDGKAALDH1A1CES1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304395-A | Mixing with dispersion of polymer based on vinyl aromatic monomer, unsaturated ester, sulfonate, unsaturated acid | STAMICARBON B.V. (NL) | 1994-04-19 | — | — | US | disclosed |
| US-4215027-A | Aqueous thermosettable coating compositions comprising aqueous copolymer latex, amine neutralized copolymer and melamine-formaldehyde resin | CANADIAN INDUSTRIES LIMITED (CA) | 1980-07-29 | — | — | US | disclosed |
| US-4075134-A | EMULSION POLYMERIZATION METHOD FOR PREPARING MICROSPHERES HAVING LIQUID CENTER AND SEAMLESS RIGID WALLS | THE DOW CHEMICAL COMPANY (US) | 1978-02-21 | — | — | US | disclosed |
| US-4049604-A | Emulsion polymerization method for preparing aqueous dispersions of organic polymer particles | THE DOW CHEMICAL COMPANY (US) | 1977-09-20 | — | — | US | disclosed |
| US-3992333-A | NITROGEN AND SULFUR CONTAINING COPOLYMER IS SELF-CROSSLINKING BINDER | ROHM AND HAAS COMPANY (US) | 1976-11-16 | — | — | US | disclosed |
| US-3950294-A | AQUEOUS COATING COMPOSITIONS OF DISPERSIONS OF THERMOPLASTIC ADDITION POLYMERS WITH LOW MOLECULAR WEIGHT PLASTICIZERS | CONNELLY WILLIAM | 1976-04-13 | — | — | US | disclosed |