Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.96 |
| ▸ | MAPT | P10636 | 1/20 | 0.96 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.62 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.62 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.62 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.53 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.50 |
| ▸ | ADH5 | P11766 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159406 | 0.98 | LMNA (1.00) | LMNAMAPTENPP2MKNK1MKNK2 | |
| Hydrochloric Acid SCHEMBL8339879 | 0.96 | LMNA (0.96) | LMNAMAPTENPP2MKNK1MKNK2 | |
| Hydrochloric Acid SCHEMBL3565712 | 0.96 | LMNA (0.96) | LMNAMAPTENPP2MKNK1MKNK2 | |
| SCHEMBL28046707 | 0.96 | LMNA (0.96) | LMNAMAPTENPP2MKNK1MKNK2 | |
| SCHEMBL28046704 | 0.96 | LMNA (0.96) | LMNAMAPTENPP2MKNK1MKNK2 | |
| Hydrochloric Acid SCHEMBL28420692 | 0.96 | LMNA (0.96) | LMNAMAPTENPP2MKNK1MKNK2 | |
| SCHEMBL5836930 | 0.87 | MAPT (0.79) | LMNAMAPTENPP2MKNK1MKNK2 | |
| SCHEMBL10126954 | 0.87 | LMNA (0.79) | LMNAMAPTENPP2MKNK1MKNK2 | |
| SCHEMBL2532397 | 0.87 | LMNA (0.78) | LMNAMAPTENPP2MKNK1MKNK2 | |
| SCHEMBL6324509 | 0.84 | MAPT (0.74) | LMNAMAPTENPP2MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105126910-A | C2-symmetric imidazolephenyl rare earth metal catalyst, preparation method and application | BEIJING INST TECHNOLOGY | 2015-12-09 | — | — | CN | disclosed |