Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | CTSA | P10619 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 2/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27882253 | 0.84 | EGFR (0.50) | KMOHDAC1EGFRCTSACNR1 | |
| SCHEMBL725162 | 0.84 | KMO (0.62) | KMOHDAC1EGFRPLAULMNA | |
| SCHEMBL30274913 | 0.81 | ALDH1A1 (0.57) | KMOHDAC1EGFRCTSACNR1 | |
| SCHEMBL2935534 | 0.81 | PLAU (0.54) | KMOHDAC1EGFRPLAUFDPS | |
| SCHEMBL29735324 | 0.81 | PLAU (0.54) | KMOHDAC1EGFRPLAUFDPS | |
| SCHEMBL27847068 | 0.79 | CCNC (0.62) | KMOHDAC1EGFRCTSACNR1 | |
| SCHEMBL25262251 | 0.77 | CTSA (0.53) | HDAC1EGFRCTSAPLAUFDPS | |
| SCHEMBL29735406 | 0.77 | ALDH1A1 (0.51) | HDAC1EGFRCTSALMNA | |
| SCHEMBL13187686 | 0.77 | HDAC8 (0.54) | HDAC1EGFRCTSAFDPSUSP30 | |
| SCHEMBL12468522 | 0.77 | CNR2 (0.54) | KMOHDAC1EGFRCTSAPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105153190-B | Heterocycle miazines compound of the amide structure containing biaryl and its preparation method and application | 江西科技师范大学 | 2017-07-21 | — | — | CN | disclosed |
| CN-105153190-A | Biaryl amide structure containing heterocyclopyrimidine compound as well as preparation method and applications thereof | UNIV JIANGXI NORMAL SCI & TECH | 2015-12-16 | — | — | CN | disclosed |