Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | BID | P55957 | 3/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.43 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28231528 | 0.96 | ALDH1A1 (0.64) | ALDH1A1KDM4EMEN1KMT2ATLR8 | |
| SCHEMBL28992969 | 0.90 | ALDH1A1 (0.68) | ALDH1A1KDM4EMEN1KMT2ATLR8 | |
| SCHEMBL28992953 | 0.85 | ALDH1A1 (0.73) | ALDH1A1KDM4EMEN1KMT2ATLR8 | |
| SCHEMBL19841051 | 0.84 | TLR8 (0.60) | ALDH1A1KDM4EMEN1KMT2ATLR8 | |
| SCHEMBL28521009 | 0.81 | TLR8 (0.52) | ALDH1A1KDM4EMEN1KMT2ATLR8 | |
| SCHEMBL28230590 | 0.80 | TLR8 (0.55) | ALDH1A1KDM4EMEN1KMT2ATLR8 | |
| SCHEMBL29145038 | 0.79 | TLR8 (0.68) | ALDH1A1KDM4EMEN1KMT2ATLR8 | |
| SCHEMBL28551188 | 0.78 | TLR8 (0.66) | ALDH1A1KDM4EMEN1KMT2ATLR8 | |
| SCHEMBL4583699 | 0.77 | ALDH1A1 (1.00) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL168398 | 0.77 | TLR8 (0.69) | ALDH1A1KDM4ETLR8MAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085613-A | Novel thiostrepton analogue, and preparation method and application thereof | SHANGHAI INST ORGANIC CHEM | 2015-11-25 | — | — | CN | disclosed |