Diphenylether

Diphenylether

SCHEMBL28046907

[SiH3]C1C=Cc2cccc3cccc1c23.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.36
TSHR P16473 1/20 0.36
MAOB P27338 1/20 0.32
HTR1A P08908 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
NR1H2 P55055 1/20 0.31
BAX Q07812 1/20 0.31
MAOA P21397 1/20 0.31
KDM1A O60341 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17289469 0.87 ALDH1A1 (0.33) TSHR
SCHEMBL26136269 0.75 SLC6A2 (0.33) SLC6A2SLC6A4SLC6A3KDM4EMAPT
SCHEMBL962243 0.74 PARP10 (0.40) KDM4EMAPTTDP1
SCHEMBL28732733 0.74
SCHEMBL28670717 0.72 KDM4E (0.30) KDM4EMAPTTDP1
SCHEMBL27540525 0.71 TDP1 (0.45) KDM4EMAPTTDP1
SCHEMBL4652396 0.70 HTR2A (0.41) SLC6A2SLC6A3KDM4EMAPT
SCHEMBL28491194 0.70 KDM4E (0.32) KDM4EMAPTTDP1
SCHEMBL3470484 0.69 MEN1 (0.37) TSHRMAPT
SCHEMBL11035480 0.69 ALDH1A1 (0.36) TSHRKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-206516558-U Novel vacuum interrupter 七七七电气科技有限公司 2017-09-22 CN claimed
CN-106349610-A High-strength sealing gasket and preparing method thereof 郑瀚 2017-01-25 CN disclosed
CN-105802231-A High-tearing-strength silicone rubber sealing gasket and preparing method thereof 安徽精机械设备有限公司 2016-07-27 CN disclosed
CN-105331113-A Anti-static flame-retardant silicon rubber and preparation method thereof SUZHOU XINDEJIE ELECTRONICS CO LTD 2016-02-17 CN disclosed