SCHEMBL962243

SCHEMBL962243

O=C(c1ccc(Oc2ccccc2)cc1)C1C=Cc2cccc3cccc1c23

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.40
SRD5A2 P31213 4/20 0.39
MGLL Q99685 1/20 0.38
BCL2 P10415 1/20 0.36
MCL1 Q07820 1/20 0.36
BAD Q92934 1/20 0.36
AKR1C3 P42330 1/20 0.36
ERCC5 P28715 1/20 0.36
FEN1 P39748 1/20 0.36
GRM5 P41594 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPK1 P28482 1/20 0.36
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NR1H4 Q96RI1 1/20 0.34
KDM2B Q8NHM5 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27870906 0.88 EPHX1 (0.42) MGLLALDH1A1MAPK1KDM4EMAPT
Urea SCHEMBL27977094 0.84 EPHX1 (0.40) ALDH1A1MAPK1MAPTTDP1SMN1; SMN2
SCHEMBL2850466 0.83 CTNNB1 (0.43) ALDH1A1MAPK1KDM4EMAPTTDP1
SCHEMBL27540525 0.80 TDP1 (0.45) ALDH1A1KDM4EMAPTTDP1SMN1; SMN2
SCHEMBL12153022 0.76 HSD17B10 (0.34) KDM4EMAPTTDP1
SCHEMBL1272762 0.75 HSD17B10 (0.32) MCL1ALDH1A1MAPT
SCHEMBL28516568 0.74 ATM (0.36) ALDH1A1MAPK1MAPTTDP1SMN1; SMN2
Diphenylether SCHEMBL28046907 0.74 LTA4H (0.36) KDM4EMAPTTDP1
SCHEMBL547973 0.74 HSD17B10 (0.33)
SCHEMBL25567842 0.73 ATM (0.42) MCL1ALDH1A1MAPK1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9127129-B2 Star polymer ROBERT BOSCH GMBH (DE) 2015-09-08 US claimed
US-20120238699-A1 STAR POLYMER ROBERT BOSCH GMBH (DE) 2012-09-20 US claimed
US-9127129-B2 Star polymer ROBERT BOSCH GMBH (DE) 2015-09-08 US disclosed
US-20120238699-A1 STAR POLYMER ROBERT BOSCH GMBH (DE) 2012-09-20 US disclosed
EP-2456812-A1 STAR POLYMER Robert Bosch GmbH (DE) 2012-05-30 EP disclosed
WO-2011009949-A1 STAR POLYMER ROBERT BOSCH GMBH (DE) 2011-01-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120238699-A1 STAR POLYMER STARD3, STARD10, STARD7 PARP10 149/4885SRD5A2 1235/4885MGLL 3747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.