Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 8/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3684197 | 0.84 | ALDH1A1 (0.45) | PARP1LMNAPARP2ALDH1A1MAPT | |
| SCHEMBL28045651 | 0.80 | GABRA1 (0.46) | LMNAGABRA1GABRB2ANPEPDPP4 | |
| SCHEMBL28046983 | 0.76 | NPC1 (0.54) | PARP1LMNAPARP2HTTALDH1A1 | |
| SCHEMBL19554755 | 0.76 | PARP1 (0.40) | PARP1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10074345 | 0.76 | ALDH1A1 (0.43) | PARP1LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL5784795 | 0.75 | ADORA2A (0.43) | PARP1LMNAHTTALDH1A1KMT2A | |
| SCHEMBL28204617 | 0.75 | PARP1 (0.46) | PARP1LMNAPARP2HTTALDH1A1 | |
| SCHEMBL7854456 | 0.75 | PARP1 (0.42) | PARP1LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL72113 | 0.74 | PARP1 (0.49) | PARP1LMNAPARP2HTTALDH1A1 | |
| SCHEMBL9283302 | 0.74 | HTR2C (0.50) | PARP1PARP2HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105541777-A | Isoflavone amide type derivative, preparation method and medical application thereof | UNIV CHINA PHARMA | 2016-05-04 | — | — | CN | disclosed |