Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | VNN1 | O95497 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.49 |
| ▸ | FABP4 | P15090 | 1/20 | 0.49 |
| ▸ | ACP1 | P24666 | 1/20 | 0.48 |
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2448005 | 0.87 | MAPT (0.52) | PTGS2MAPTTP53VNN1PTGDR | |
| SCHEMBL28046990 | 0.84 | PTGS2 (0.49) | PTGS2MAPTTP53VNN1FABP4 | |
| SCHEMBL2087964 | 0.83 | ACP1 (0.64) | PTGS2MAPTTP53PTGDRACP1 | |
| SCHEMBL20651456 | 0.80 | MEN1 (0.53) | PTGS2MAPTTP53MEN1KMT2A | |
| SCHEMBL4300168 | 0.79 | MEN1 (0.56) | MAPTTP53MEN1KMT2APTGDR | |
| SCHEMBL2448924 | 0.79 | USP1 (0.55) | PTGS2MAPTTP53MEN1KMT2A | |
| SCHEMBL31349645 | 0.78 | MAPT (0.63) | PTGS2MAPTTP53MEN1KMT2A | |
| SCHEMBL953773 | 0.77 | TSHR (0.56) | MAPTTP53MEN1KMT2AVNN1 | |
| SCHEMBL30302016 | 0.76 | MAPT (0.60) | PTGS2MAPTTP53VNN1PTGDR | |
| SCHEMBL24272902 | 0.76 | PTGS2 (0.49) | PTGS2MAPTTP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105541792-A | Polycyclic PI3K inhibitors | XUANZHU PHARMA CO LTD | 2016-05-04 | — | — | CN | disclosed |