Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.43 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | PPARD | Q03181 | 4/20 | 0.38 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28779420 | 0.98 | GPR84 (0.46) | GPR84HSPD1BLMHSPE1PPARG | |
| SCHEMBL27997511 | 0.98 | GPR84 (0.46) | GPR84HSPD1BLMHSPE1PPARG | |
| SCHEMBL24667111 | 0.84 | GPR84 (0.46) | GPR84HSPD1BLMHSPE1PPARG | |
| SCHEMBL28248774 | 0.84 | GPR84 (0.46) | GPR84HSPD1BLMHSPE1PPARG | |
| SCHEMBL414048 | 0.80 | GPR84 (0.42) | GPR84HSPD1BLMHSPE1AKR1B1 | |
| SCHEMBL24401338 | 0.79 | GPR84 (0.40) | GPR84HSPD1BLMHSPE1AKR1B1 | |
| SCHEMBL11790218 | 0.79 | GPR84 (0.44) | GPR84HSPD1BLMHSPE1PPARG | |
| SCHEMBL8968596 | 0.79 | HSPD1 (0.47) | GPR84HSPD1BLMHSPE1PPARG | |
| SCHEMBL8375187 | 0.79 | GPR84 (0.41) | GPR84HSPD1BLMHSPE1AKR1B1 | |
| SCHEMBL29128602 | 0.79 | GPR84 (0.44) | GPR84HSPD1BLMHSPE1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105121430-A | Modulators of the retinoid-related orphan receptor gamma (ror-gamma) for use in the treatment of autoimmune and inflammatory diseases | GLAXO GROUP LTD | 2015-12-02 | — | — | CN | disclosed |