Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1959602 | 0.66 | HTR2C (0.39) | MAPT | |
| SCHEMBL6432296 | 0.66 | PRCP (0.36) | ALDH1A1SLC6A3ADORA2A | |
| SCHEMBL1076869 | 0.63 | SLC6A3 (0.52) | MAPTSMN1; SMN2SLC6A3GSK3AGSK3B | |
| Bromide SCHEMBL7376258 | 0.62 | SLC6A3 (0.40) | MAPTSLC6A3GSK3AGSK3BMGLL | |
| Bromide SCHEMBL1077951 | 0.62 | SLC6A3 (0.50) | MAPTSMN1; SMN2SLC6A3GSK3AGSK3B | |
| Iodide SCHEMBL9160115 | 0.62 | SLC6A3 (0.50) | MAPTSMN1; SMN2SLC6A3GSK3AGSK3B | |
| SCHEMBL2913069 | 0.60 | GAA (0.47) | ALDH1A1MAPTRAB9ASLC6A3SIGMAR1 | |
| SCHEMBL5778051 | 0.60 | SLC6A3 (0.48) | SLC6A3HRH3SIGMAR1 | |
| SCHEMBL29883119 | 0.59 | KMT2A (0.63) | ALDH1A1MAPTRAB9ASMN1; SMN2SIGMAR1 | |
| SCHEMBL30474228 | 0.59 | PNMT (0.56) | ALDH1A1MAPTRAB9ASLC6A3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105164134-A | Imidazo-triazine derivatives as pde10 inhibitors | PFIZER | 2015-12-16 | — | — | CN | disclosed |