Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10043022 | 0.84 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1CYP1A2HRH1KMT2A | |
| SCHEMBL13684596 | 0.84 | — | — | |
| SCHEMBL13229795 | 0.83 | LMNA (0.58) | SMN1; SMN2MEN1CYP1A2HRH1KMT2A | |
| SCHEMBL9189914 | 0.78 | LMNA (0.68) | SMN1; SMN2MEN1CYP1A2HRH1KMT2A | |
| SCHEMBL19361541 | 0.77 | — | — | |
| SCHEMBL988073 | 0.77 | — | — | |
| SCHEMBL14288711 | 0.74 | TSHR (0.37) | SMN1; SMN2MEN1CYP1A2HRH1KMT2A | |
| SCHEMBL1020470 | 0.74 | TDP1 (0.53) | SMN1; SMN2MEN1CYP1A2HRH1KMT2A | |
| Hydrochloric Acid SCHEMBL4305679 | 0.72 | TDP1 (0.52) | SMN1; SMN2MEN1CYP1A2HRH1KMT2A | |
| SCHEMBL24951337 | 0.71 | CYP1A2 (0.41) | SMN1; SMN2MEN1CYP1A2HRH1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105308049-A | Spiro-lactam nmda receptor modulators and uses thereof | NAUREX INC | 2016-02-03 | — | — | CN | disclosed |