Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13684596 | 0.85 | — | — | |
| SCHEMBL28047126 | 0.84 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAMEN1CYP1A2HRH1 | |
| SCHEMBL13229795 | 0.84 | LMNA (0.58) | SMN1; SMN2LMNAMEN1CYP1A2HRH1 | |
| SCHEMBL27638914 | 0.80 | TDP1 (0.48) | SMN1; SMN2LMNAMEN1CYP1A2HRH1 | |
| SCHEMBL988073 | 0.79 | — | — | |
| SCHEMBL19361541 | 0.79 | — | — | |
| SCHEMBL12122789 | 0.77 | TSHR (0.34) | SMN1; SMN2LMNAMEN1CYP1A2HRH1 | |
| SCHEMBL14288711 | 0.76 | TSHR (0.37) | SMN1; SMN2LMNAMEN1CYP1A2HRH1 | |
| SCHEMBL1020470 | 0.76 | TDP1 (0.53) | SMN1; SMN2LMNAMEN1CYP1A2HRH1 | |
| Hydrochloric Acid SCHEMBL4305679 | 0.74 | TDP1 (0.52) | SMN1; SMN2LMNAMEN1CYP1A2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9334235-B2 | Plasmalogen compounds, pharmaceutical compositions containing the same and methods for treating diseases of the aging | PHENOMENOME DISCOVERIES INC. (CA) | 2016-05-10 | — | — | US | disclosed |
| US-9334235-B2 | Plasmalogen compounds, pharmaceutical compositions containing the same and methods for treating diseases of the aging | PHENOMENOME DISCOVERIES INC. (CA) | 2016-05-10 | — | — | US | disclosed |
| US-20130116312-A2 | PLASMALOGEN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND METHODS FOR TREATING DISEASES OF THE AGING | PHENOMENOME DISCOVERIES INC. (CA) | 2013-05-09 | — | — | US | disclosed |
| US-20130116312-A2 | PLASMALOGEN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND METHODS FOR TREATING DISEASES OF THE AGING | PHENOMENOME DISCOVERIES INC. (CA) | 2013-05-09 | — | — | US | disclosed |
| US-20120035250-A1 | PLASMALOGEN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND METHODS FOR TREATING DISEASES OF THE AGING | PHENOMENOME DISCOVERIES INC. (CA) | 2012-02-09 | — | — | US | disclosed |
| US-20120035250-A1 | PLASMALOGEN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND METHODS FOR TREATING DISEASES OF THE AGING | PHENOMENOME DISCOVERIES INC. (CA) | 2012-02-09 | — | — | US | disclosed |
| WO-2010071988-A1 | PLASMALOGEN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND METHODS FOR TREATING DISEASES OF THE AGING | PHENOMENOME DISCOVERIES INC. (CA) | 2010-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035250-A1 | PLASMALOGEN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND METHODS FOR TREATING DISEASES OF THE AGING | PHOSPHO1, SGMS2, MBOAT1 | SMN1; SMN2 342/4885LMNA 1183/4885MEN1 341/4885 |
| US-20130116312-A2 | PLASMALOGEN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND METHODS FOR TREATING DISEASES OF THE AGING | PHOSPHO1, SGMS2, MBOAT1 | SMN1; SMN2 342/4885LMNA 1183/4885MEN1 341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.