Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 17/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28825220 | 0.84 | KLKB1 (0.56) | KLKB1NR1I2KCNH2GRM2KLK1 | |
| SCHEMBL28047227 | 0.84 | KLKB1 (0.55) | KLKB1NR1I2KCNH2GRM2KLK1 | |
| SCHEMBL16246805 | 0.84 | KLKB1 (0.62) | KLKB1HSD17B10KLK1L3MBTL1 | |
| SCHEMBL28047222 | 0.83 | KLKB1 (0.49) | KLKB1HSD17B10NR1I2KCNH2GRM2 | |
| SCHEMBL28047272 | 0.80 | KLKB1 (0.65) | KLKB1HSD17B10KLK1 | |
| SCHEMBL28047231 | 0.80 | KLKB1 (0.58) | KLKB1NR1I2KCNH2GRM2KLK1 | |
| SCHEMBL19087149 | 0.77 | HSD17B10 (0.70) | KLKB1HSD17B10L3MBTL1 | |
| SCHEMBL948453 | 0.77 | HSD17B10 (0.61) | KLKB1HSD17B10L3MBTL1 | |
| SCHEMBL28047220 | 0.74 | KLKB1 (0.63) | KLKB1KLK1 | |
| SCHEMBL17696410 | 0.74 | KLKB1 (0.55) | KLKB1HSD17B10KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143201-A | Benzylamine derivatives | KALVISTA PHARMACEUTICALS LTD | 2015-12-09 | — | — | CN | claimed |
| CN-105143201-A | Benzylamine derivatives | KALVISTA PHARMACEUTICALS LTD | 2015-12-09 | — | — | CN | disclosed |