Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 19/20 | 0.55 |
| ▸ | KLK1 | P06870 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16246696 | 0.86 | KLKB1 (0.66) | KLKB1KLK1 | |
| SCHEMBL28825217 | 0.85 | KLKB1 (0.54) | KLKB1KLK1NR1I2KCNH2GRM2 | |
| SCHEMBL28047174 | 0.84 | KLKB1 (0.50) | KLKB1KLK1NR1I2KCNH2GRM2 | |
| SCHEMBL28047169 | 0.82 | KLKB1 (0.68) | KLKB1KLK1 | |
| SCHEMBL28825220 | 0.79 | KLKB1 (0.56) | KLKB1KLK1NR1I2KCNH2GRM2 | |
| SCHEMBL28825216 | 0.76 | KLKB1 (0.65) | KLKB1KLK1 | |
| SCHEMBL28047231 | 0.75 | KLKB1 (0.58) | KLKB1KLK1NR1I2KCNH2GRM2 | |
| SCHEMBL28047224 | 0.75 | KLKB1 (0.65) | KLKB1KLK1 | |
| SCHEMBL16246792 | 0.73 | KLKB1 (0.61) | KLKB1KLK1 | |
| SCHEMBL15965171 | 0.73 | KLKB1 (0.47) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143201-A | Benzylamine derivatives | KALVISTA PHARMACEUTICALS LTD | 2015-12-09 | — | — | CN | claimed |
| CN-105143201-A | Benzylamine derivatives | KALVISTA PHARMACEUTICALS LTD | 2015-12-09 | — | — | CN | disclosed |