Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | CTSA | P10619 | 2/20 | 0.44 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15544242 | 0.84 | KCNH2 (0.54) | KDM1AHDAC1HDAC6KCNH2 | |
| SCHEMBL31418086 | 0.81 | KDM1A (0.48) | ERN1CYP11B1CYP11B2KDM1AHDAC1 | |
| SCHEMBL15937905 | 0.80 | ERN1 (0.54) | ERN1PTPRCPTPN1ALDH1A1TSHR | |
| SCHEMBL3748536 | 0.78 | CYP11B2 (0.43) | ERN1CYP11B1CYP11B2KDM1A | |
| SCHEMBL9910946 | 0.78 | PDGFRB (0.53) | PDGFRBPDGFRACYP11B1CYP11B2PTPRC | |
| SCHEMBL2009055 | 0.77 | DRD1 (0.63) | ERN1PTPRCPTPN1ALDH1A1TSHR | |
| SCHEMBL7391983 | 0.76 | PDGFRB (0.51) | PDGFRBPDGFRACYP11B1CYP11B2PTPRC | |
| SCHEMBL1119500 | 0.76 | PDGFRB (0.51) | PDGFRBPDGFRACYP11B1CYP11B2PTPRC | |
| SCHEMBL3363703 | 0.76 | PDGFRB (0.51) | PDGFRBPDGFRACYP11B1CYP11B2PTPRC | |
| SCHEMBL29066311 | 0.76 | CYP11B1 (0.48) | ERN1CYP11B1CYP11B2KDM1AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143216-A | Antibacterial biaromatic derivatives | ACTELION PHARMACEUTICALS LTD | 2015-12-09 | — | — | CN | disclosed |