Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9910946 | 0.81 | PDGFRB (0.53) | PDGFRBPDGFRACYP11B1CYP11B2HSD17B10 | |
| SCHEMBL3457094 | 0.81 | NCOA1 (0.57) | CHRNB4CHRNA3FEN1FYNKCNH2 | |
| SCHEMBL7391983 | 0.80 | PDGFRB (0.51) | PDGFRBPDGFRACYP11B1CYP11B2HSD17B10 | |
| SCHEMBL1119500 | 0.80 | PDGFRB (0.51) | PDGFRBPDGFRACYP11B1CYP11B2HSD17B10 | |
| SCHEMBL3399384 | 0.77 | LCK (0.46) | CHRNB4CHRNA3HSD17B10ALOX5APFEN1 | |
| SCHEMBL1039794 | 0.77 | HTR7 (0.55) | DHFRMAP4K4HSD17B10ALOX5APFEN1 | |
| SCHEMBL20812402 | 0.77 | KIT (0.72) | NTRK1KITPIK3CA | |
| SCHEMBL6754272 | 0.77 | CYP1A2 (0.54) | PDGFRBPDGFRAHSD17B10ALDH1A1KDM4E | |
| SCHEMBL2554408 | 0.76 | PDGFRB (0.48) | PDGFRBPDGFRACYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL28047285 | 0.76 | ERN1 (0.50) | PDGFRBPDGFRACYP11B1CYP11B2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101801931-B | Azabiphenylaminobenzoic acid derivatives as dhodh inhibitors | ALMIRALL SA | 2014-05-14 | — | — | CN | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |