SCHEMBL28047314

SCHEMBL28047314

O=C(Cc1ccccc1)C1(O)C=CC(O)=CC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.39
CES2 O00748 1/20 0.39
AKR1B1 P15121 1/20 0.39
FNTA P49354 1/20 0.38
FNTB P49356 1/20 0.38
MAPK1 P28482 2/20 0.37
ALDH1A1 P00352 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
PAM P19021 1/20 0.36
EPHX2 P34913 2/20 0.36
HDAC8 Q9BY41 2/20 0.35
HDAC6 Q9UBN7 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
HDAC3 O15379 1/20 0.35
ADRA1A P35348 1/20 0.35
HDAC4 P56524 1/20 0.35
SLC6A3 Q01959 1/20 0.35
HDAC1 Q13547 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10456255 0.75 CES1 (0.41) CES1CES2AKR1B1FNTAFNTB
SCHEMBL27999703 0.73
SCHEMBL29190936 0.67 MAOA (0.35) ALDH1A1MEN1KMT2A
SCHEMBL13704034 0.66 CES2 (0.38) CES1CES2AKR1B1MAPK1ALDH1A1
SCHEMBL347447 0.65 AKR1C1 (0.38) HDAC4HDAC9HTT
SCHEMBL10608700 0.64 CES1 (0.47) CES1CES2AKR1B1FNTAFNTB
SCHEMBL29190924 0.64 POLB (0.33) CES1ALDH1A1GAA
SCHEMBL8391946 0.63 CES1 (0.50) CES1CES2AKR1B1FNTAFNTB
SCHEMBL8391674 0.60 CES1 (0.47) CES1CES2AKR1B1FNTAFNTB
SCHEMBL8392962 0.60 CES1 (0.47) CES1CES2AKR1B1FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-204918447-U Novel production of 7 - hydroxyl isoflavone device XINYI WANYU INDUSTRY AND TRADE CO LTD 2015-12-30 CN disclosed